p70 S6 Kinase 1 Rabbit Monoclonal Antibody (CAB4898)
- SKU:
- CAB4898
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | p70 S6 Kinase 1 Rabbit Monoclonal Antibody |
SKU: | CAB4898 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p70 S6 Kinase 1 (NP_003152.1). |
Sequence: | MRRR RRRD GFYP APDF RDRE AEDM AGVF DIDL DQPE DAGS EDEL EEGG QLNE SMDH GGVG PYEL GMEH CEKF EISE TSVN RGPE KIRP ECFE LLRV LGKG |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha; p70 S6 Kinase 1 |
Positive Sample: | HeLa,293T,Jurkat,Mouse brain,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cytoplasm, Mitochondrion outer membrane, Mitochondrion, Nucleus, synapse, synaptosome. |
Calculated MW: | 59kDa |
Observed MW: | 68kDa/75kDa |
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Purification Method: | Affinity purification |
Gene ID: | 6198 |
Clone Number: | ARC57223 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |