p53 Monoclonal Antibody [PP53SHG] (CPAB0491)
- SKU:
- CPAB0491
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PP53SHG
- Applications:
- WB
Description
p53 Monoclonal Antibody [PP53SHG] (CPAB0491)
The p53 Polyclonal Antibody (CPAB0491) offered by AssayGenie is a valuable tool for researchers studying the p53 protein, a key player in the regulation of cell growth and apoptosis. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in Western blot applications.The p53 protein, also known as the "guardian of the genome," is a tumor suppressor that plays a crucial role in preventing cancer development by promoting cell cycle arrest and DNA repair or inducing programmed cell death.
Dysregulation of p53 function is commonly observed in various types of cancer, making it a target of interest in cancer research.By using the p53 Polyclonal Antibody, researchers can detect and analyze p53 protein levels in different cell types, helping to further our understanding of its role in cancer development and progression. This antibody is a valuable tool for studies aiming to uncover novel therapeutic targets and develop targeted therapies for cancer treatment.
Product Name: | p53 Antibody |
Product Sku: | CPAB0491 |
Size: | 100μg |
Host Species: | Mouse |
Immunogen: | |
Clone: | PP53SHG. |
Reactivity: | Other bodies |
Applications: | Western Blot |
Purification Method: | |
Isotype: | IgG2a |
Background: | p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma. |
Synonyms: | |
Storage Buffer: |