P4HA1 Rabbit Polyclonal Antibody (CAB10538)
- SKU:
- CAB10538
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | P4HA1 Rabbit Polyclonal Antibody |
SKU: | CAB10538 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 235-534 of human P4HA1 (NP_001017962.1). |
Sequence: | DPEH QRAN GNLK YFEY IMAK EKDV NKSA SDDQ SDQK TTPK KKGV AVDY LPER QKYE MLCR GEGI KMTP RRQK KLFC RYHD GNRN PKFI LAPA KQED EWDK PRII RFHD IISD AEIE IVKD LAKP RLRR ATIS NPIT GDLE TVHY RISK SAWL SGYE NPVV SRIN MRIQ DLTG LDVS TAEE LQVA NYGV GGQY EPHF DFAR KDEP DAFK ELGT GNRI ATWL FYMS DVSA GGAT VFPE VGAS VWPK KGTA VFWY NLFA SGEG DYST RHAA CPVL VGNK WVSN KWLH ERGQ EFRR PCTL SELE |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | P4HA; P4HA1 |
Positive Sample: | HepG2,NCI-H460,U-251MG,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum lumen. |
Calculated MW: | 61kDa |
Observed MW: | 61kDa |
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 5033 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |