The P2Y6 Rabbit Monoclonal Antibody (CAB3708) is a valuable tool for researchers studying P2Y6, a member of the purinergic receptor family known for its involvement in various physiological processes. This antibody, derived from rabbit monoclonal cells, exhibits high specificity and sensitivity when detecting P2Y6 in human samples, making it a reliable choice for Western blot applications.P2Y6 is a G protein-coupled receptor that responds to extracellular nucleotides, playing a role in immune responses, inflammation, and cell proliferation. Its activation has been implicated in numerous diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions.
By targeting P2Y6 with this antibody, researchers can gain insights into its function and potential as a therapeutic target for various pathologies.With its ability to detect and analyze P2Y6 in a variety of cell types, the P2Y6 Rabbit Monoclonal Antibody (CAB3708) is a valuable asset for studies in pharmacology, neurobiology, and cancer research. By elucidating the mechanisms of P2Y6 signaling, researchers can pave the way for the development of novel treatments and interventions aimed at modulating purinergic receptor activity for therapeutic benefit.
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method:
Affinity purification
Gene ID:
5031
Clone Number:
ARC0831
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Purinergic Receptor Purinergic Receptor P2Y6 Rabbit mAb (CAB3708) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
