The P2Y Purinoceptor 6 Polyclonal Antibody (CAB2485) is a valuable tool for researchers studying purinergic signaling pathways. This antibody, generated in rabbits, specifically targets the P2Y purinoceptor 6 protein and is highly reactive with human samples. Validated for use in Western blot applications, the antibody allows for the detection and analysis of P2Y purinoceptor 6 in various cell types.P2Y purinoceptor 6 is a G protein-coupled receptor that responds to extracellular nucleotides, playing a crucial role in processes such as platelet aggregation, inflammation, and neurotransmission.
By targeting this receptor with the CAB2485 antibody, researchers can gain insights into its function and potential implications in various physiological and pathological conditions.With the growing interest in purinergic signaling and its involvement in diseases such as cancer, autoimmune disorders, and neurological conditions, the P2Y Purinoceptor 6 Polyclonal Antibody (CAB2485) serves as a valuable tool for advancing research in these areas. Its specificity and reliability make it an essential component in immunology and cell biology studies focused on purinergic receptors.
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method:
Affinity purification
Gene ID:
5031
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse lung, using Purinergic Receptor P2Y6 Rabbit pAb (CAB2485) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
