The P2Y Purinoceptor 4 Polyclonal Antibody (CAB3059) is formulated for research purposes involving P2Y purinoceptor 4, a cell surface receptor known for its role in purinergic signaling pathways and immune responses. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for compatibility with Western blot applications. Its specificity allows for precise detection and analysis of the P2Y purinoceptor 4 protein in a variety of cell types, making it an ideal tool for studies in immunology and cellular signaling research.
P2Y purinoceptor 4 is a key player in purinergic signaling, which influences processes such as inflammation, cell proliferation, and neurotransmission. Its involvement in immune responses and communication between cells highlights its importance in understanding various physiological and pathological conditions. Research into P2Y purinoceptor 4 may provide insights into diseases related to immune dysregulation, such as inflammatory disorders and cancer, as well as potential therapeutic strategies targeting purinergic signaling pathways.
Product Name:
P2RY4 Rabbit Polyclonal Antibody
SKU:
CAB3059
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 286-365 of human P2RY4 (NP_002556.1).
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.
Purification Method:
Affinity purification
Gene ID:
5030
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using P2RY4 antibody (CAB3059) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
