The P2Y Purinoceptor 2 Polyclonal Antibody (CAB5779) is a vital tool for researchers studying purinoceptor signaling pathways and their role in various physiological and pathological processes. This antibody, produced in rabbits, displays high sensitivity and specificity in detecting P2Y Purinoceptor 2 protein in human samples, making it ideal for use in Western blot applications.P2Y Purinoceptor 2 is a G protein-coupled receptor involved in mediating cellular responses to extracellular nucleotides, such as ATP and ADP. Its activation plays a crucial role in diverse cellular functions, including neurotransmission, inflammation, and platelet aggregation.
By targeting P2Y Purinoceptor 2, researchers can unravel the intricate mechanisms underlying purinergic signaling and explore its implications in conditions like cardiovascular diseases, neurological disorders, and cancer.With its ability to accurately detect and quantify P2Y Purinoceptor 2 expression in a variety of cell types, the CAB5779 antibody is invaluable for studies investigating the function and regulation of this receptor. Its utility extends to drug development efforts aimed at exploiting purinergic signaling pathways as therapeutic targets for treating a wide range of diseases.
Product Name:
P2RY2 Rabbit Polyclonal Antibody
SKU:
CAB5779
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 278-377 of human P2RY2 (NP_002555.4).
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
5029
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse skeletal muscle, using P2RY2 Rabbit pAb (CAB5779) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
