P2RY1 Rabbit Polyclonal Antibody (CAB7706)
- SKU:
- CAB7706
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | P2RY1 Rabbit Polyclonal Antibody |
SKU: | CAB7706 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 274-373 of human P2RY1 (NP_002554.1). |
Sequence: | IPFH VMKT MNLR ARLD FQTP AMCA FNDR VYAT YQVT RGLA SLNS CVDP ILYF LAGD TFRR RLSR ATRK ASRR SEAN LQSK SEDM TLNI LPEF KQNG DTSL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | P2Y1; SARCC; P2RY1 |
Positive Sample: | 22Rv1,Rat liver,Rat intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Purification Method: | Affinity purification |
Gene ID: | 5028 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |