P2RX7 Rabbit Polyclonal Antibody (CAB10511)
- SKU:
- CAB10511
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | P2RX7 Rabbit Polyclonal Antibody |
SKU: | CAB10511 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 47-334 of human P2RX7 (NP_002553.3). |
Sequence: | SDKL YQRK EPVI SSVH TKVK GIAE VKEE IVEN GVKK LVHS VFDT ADYT FPLQ GNSF FVMT NFLK TEGQ EQRL CPEY PTRR TLCS SDRG CKKG WMDP QSKG IQTG RCVV YEGN QKTC EVSA WCPI EAVE EAPR PALL NSAE NFTV LIKN NIDF PGHN YTTR NILP GLNI TCTF HKTQ NPQC PIFR LGDI FRET GDNF SDVA IQGG IMGI EIYW DCNL DRWF HHCR PKYS FRRL DDKT TNVS LYPG YNFR YAKY YKEN NVEK RTLI KVFG IRFD ILVF GTGG KFDI IQLV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | P2X7; P2RX7 |
Positive Sample: | Mouse lung,Mouse heart,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 69kDa |
Observed MW: | 75kDa |
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
Purification Method: | Affinity purification |
Gene ID: | 5027 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |