P2RY2 Rabbit Polyclonal Antibody (CAB13923)
- SKU:
- CAB13923
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | P2RY2 Rabbit Polyclonal Antibody |
SKU: | CAB13923 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 278-377 of human P2RY2 (NP_788086.1). |
Sequence: | CHTL NAIN MAYK VTRP LASA NSCL DPVL YFLA GQRL VRFA RDAK PPTG PSPA TPAR RRLG LRRS DRTD MQRI EDVL GSSE DSRR TEST PAGS ENTK DIRL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | P2U; HP2U; P2U1; P2UR; P2Y2; P2RU1; P2Y2R; P2RY2 |
Positive Sample: | MCF7,HL-60,THP-1,SKOV3,BT-474,Mouse liver,Mouse heart,Mouse skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 42kDa |
Observed MW: | 42-52kDa |
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5029 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |