The P2RY2 Polyclonal Antibody (CAB13923) is specifically designed for research involving the P2RY2 receptor, a cell surface receptor involved in purinergic signaling. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in Western blot applications, enabling detection and analysis of the P2RY2 protein in various cell types.P2RY2 is known to play a crucial role in mediating responses to extracellular ATP and regulating various physiological processes, including inflammation, pain sensation, and immune responses. Its significance in purinergic signaling makes it a valuable target for research into diseases like cardiovascular disorders, neurological conditions, and inflammatory diseases.
Understanding the activity of P2RY2 is essential for developing therapies that target purinergic signaling pathways in these contexts.Overall, the P2RY2 Polyclonal Antibody (CAB13923) is a valuable tool for researchers studying purinergic signaling and its role in various physiological and pathological processes. With its high reactivity and specificity, this antibody is ideal for investigations in immunology, neuroscience, and drug development.
Product Name:
P2RY2 Rabbit Polyclonal Antibody
SKU:
CAB13923
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 278-377 of human P2RY2 (NP_788086.1).
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
5029
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using P2RY2 antibody (CAB13923) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
