The P2RY11 Polyclonal Antibody (CAB16940) is specifically designed for research on P2RY11, a purinergic receptor involved in immune responses and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the P2RY11 protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal tool for studies in immunology and inflammatory diseases.P2RY11 is a key player in purinergic signaling, which has been implicated in the regulation of immune cell activation and cytokine production. Dysregulation of P2RY11 signaling has been associated with various inflammatory conditions and autoimmune diseases.
Therefore, research on P2RY11 and its role in immune modulation is crucial for developing therapeutics targeting inflammatory disorders and improving our understanding of immune response regulation. Overall, the P2RY11 Polyclonal Antibody (CAB16940) is a valuable tool for researchers looking to explore the function of P2RY11 in immune responses, inflammation, and related disease processes. Its high specificity and reactivity make it a reliable choice for studies in immunology and inflammatory research.
Product Name:
P2RY11 Rabbit Polyclonal Antibody
SKU:
CAB16940
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-379 of human P2RY11 (NP_002557.2).
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.
Purification Method:
Affinity purification
Gene ID:
5032
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using P2RY11 Rabbit pAb (CAB16940) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
