The P2Y Purinoceptor 1 Polyclonal Antibody (CAB7706) is a valuable tool for researchers studying the P2Y purinoceptor 1 protein, a receptor involved in purinergic signaling pathways. This antibody is produced in rabbits and demonstrates high reactivity with human samples, making it reliable for use in Western blot applications. By specifically binding to the P2Y purinoceptor 1 protein, this antibody enables the detection and analysis of this critical receptor in various cell types.The P2Y purinoceptor 1 protein plays a significant role in cell signaling processes related to inflammation, immune responses, and cell proliferation.
Understanding the function and activity of this receptor is essential for research into conditions such as cardiovascular diseases, neurological disorders, and immune-related conditions. The use of the P2Y Purinoceptor 1 Polyclonal Antibody (CAB7706) can facilitate insights into the mechanisms underlying these diseases and aid in the development of targeted therapeutic interventions.
Product Name:
P2RY1 Rabbit Polyclonal Antibody
SKU:
CAB7706
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 274-373 of human P2RY1 (NP_002554.1).
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Purification Method:
Affinity purification
Gene ID:
5028
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using P2RY1 antibody (CAB7706) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
