OCA2 Rabbit Polyclonal Antibody (CAB5653)
- SKU:
- CAB5653
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | OCA2 Rabbit Polyclonal Antibody |
SKU: | CAB5653 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human OCA2 (NP_000266.2). |
Sequence: | MHLE GRDG RRYP GAPA VELL QTSV PSGL AELV AGKR RLPR GAGG ADPS HSCP RGAA GQSS WAPA GQEF ASFL TKGR SHSS LPQM SSSR SKDS CFTE NTPL LRNS LQEK GSRC IPVY HPEF ITAE ESWE DSSA DWER RYLL SREV SGLS ASAS SEKG DLLD SPHI RLRL SKLR RCVQ WLKV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | P; BEY; PED; BEY1; BEY2; BOCA; EYCL; HCL3; EYCL2; EYCL3; SHEP1; D15S12; OCA2 |
Positive Sample: | 293T,U-937,Mouse eye |
Conjugate: | Unconjugated |
Cellular Localization: | Melanosome membrane, Multi-pass membrane protein. |
Calculated MW: | 93kDa |
Observed MW: | 65-80kDa |
This gene encodes the human homolog of the mouse p (pink-eyed dilution) gene. The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis. It is involved in mammalian pigmentation, where it may control skin color variation and act as a determinant of brown or blue eye color. Mutations in this gene result in type 2 oculocutaneous albinism. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4948 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |