The OXTR Polyclonal Antibody (CAB18686) is a valuable tool for researchers studying the oxytocin receptor (OXTR), a key molecule involved in various physiological processes including social behavior, stress response, and reproductive functions. This antibody is raised in rabbits and has been validated for use in Western blot applications with high reactivity towards human samples.The OXTR antibody specifically binds to the OXTR protein, allowing for the detection and analysis of OXTR expression in different cell types. This makes it an ideal choice for studies in neuroscience, endocrinology, and reproductive biology, where the role of OXTR in mediating oxytocin signaling is of particular interest.Oxytocin is a hormone and neurotransmitter that plays a critical role in social bonding, trust, and emotional regulation.
Dysregulation of the oxytocin system has been implicated in various psychiatric disorders such as autism, schizophrenia, and mood disorders. By studying the OXTR protein and its function, researchers can gain insights into the underlying mechanisms of these disorders and potentially identify new therapeutic targets for treatment.Overall, the OXTR Polyclonal Antibody (CAB18686) is a valuable tool for researchers looking to delve deeper into the role of the oxytocin receptor in health and disease, providing crucial insights that may have implications for the development of novel therapeutic strategies.
Product Name:
Oxytocin Receptor Rabbit Polyclonal Antibody
SKU:
CAB18686
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-394 of human Oxytocin Receptor (NP_000907.2).
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition.
Purification Method:
Affinity purification
Gene ID:
5021
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Oxytocin Receptor Rabbit pAb (CAB18686) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
