The OXER1 Polyclonal Antibody (PACO01614) is a valuable tool for researchers studying OXER1, a G-protein coupled receptor involved in the modulation of inflammation and lipid metabolism. This antibody, produced in rabbits, has high specificity for human samples and is validated for use in Western blot and immunohistochemistry applications.OXER1, also known as 5-oxo-ETE receptor, plays a crucial role in the regulation of inflammatory responses and has been implicated in various diseases, including atherosclerosis and asthma.
By targeting OXER1, researchers can gain insight into the pathways involved in inflammation and lipid signaling, which may lead to the development of novel therapeutic interventions.Overall, the OXER1 Polyclonal Antibody (PACO01614) is a valuable tool for researchers studying OXER1 and its implications in inflammation-related diseases. Its high reactivity and specificity make it ideal for various research applications in immunology, lipid metabolism, and disease pathology.
Antibody Name:
OXER1 Antibody
Antibody SKU:
PACO01614
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC, IF
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human TG1019.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OXER1: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1Chromosomal Location of Human Ortholog: 2p21Cellular Component: integral to membrane; plasma membraneMolecular Function: 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding; G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; regulation of cAMP biosynthetic process
