The OXCT1 Polyclonal Antibody is a crucial tool for researchers studying OXCT1, a key enzyme involved in fatty acid metabolism and energy production. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the OXCT1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in metabolism, mitochondrial function, and related diseases.OXCT1 plays a vital role in the breakdown of fatty acids for energy production, making it essential for normal metabolic function.
Dysregulation of OXCT1 has been linked to metabolic disorders such as obesity, diabetes, and cardiovascular disease, highlighting its importance in maintaining metabolic homeostasis. By understanding the role of OXCT1 in these processes, researchers can gain valuable insights into the mechanisms underlying metabolic diseases and potentially identify therapeutic targets for intervention.
Product Name:
OXCT1 Polyclonal Antibody
SKU:
CAB21844
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 261-520 of human OXCT1 (NP_000427.1).
This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
Purification Method:
Affinity purification
Gene ID:
5019
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using OXCT1 Rabbit pAb (CAB21844) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
