OTX2 Rabbit Monoclonal Antibody (CAB4351)
- SKU:
- CAB4351
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | OTX2 Rabbit Monoclonal Antibody |
SKU: | CAB4351 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 190-289 of human OTX2 (P32243). |
Sequence: | AGST SYFG GMDC GSYL TPMH HQLP GPGA TLSP MGTN AVTS HLNQ SPAS LSTQ GYGA SSLG FNST TDCL DYKD QTAS WKLN FNAD CLDY KDQT SSWK FQVL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CPHD6; MCOPS5; OTX2 |
Positive Sample: | U-251MG,Y79,Mouse eye,Rat eye |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 32kDa |
Observed MW: | 35kDa |
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.
Purification Method: | Affinity purification |
Gene ID: | 5015 |
Clone Number: | ARC0973 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |