OTX2 Rabbit Polyclonal Antibody (CAB5475)
- SKU:
- CAB5475
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | OTX2 Rabbit Polyclonal Antibody |
SKU: | CAB5475 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-280 of human OTX2 (NP_068374.1). |
Sequence: | TPPS STSV PTIA SSSA PVSI WSPA SISP LSDP LSTS SSCM QRSY PMTY TQAS GYSQ GYAG STSY FGGM DCGS YLTP MHHQ LPGP GATL SPMG TNAV TSHL NQSP ASLS TQGY GASS LGFN STTD CLDY KDQT ASWK LNFN A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CPHD6; MCOPS5; OTX2 |
Positive Sample: | Mouse liver,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 32kDa |
Observed MW: | 32kDa |
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.
Purification Method: | Affinity purification |
Gene ID: | 5015 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |