The OTUD4 Polyclonal Antibody (CAB15229) is a high-quality research tool specifically designed for studying OTUD4, a deubiquitinating enzyme involved in regulating various cellular processes. This antibody, generated in rabbits, demonstrates strong reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the OTUD4 protein, researchers can accurately detect and analyze its expression levels in a variety of cell types, making it an invaluable tool for investigations in cell biology and cancer research.OTUD4, also known as ovarian tumor domain-containing protein 4, is a key player in the ubiquitin system, where it acts to remove ubiquitin molecules from target proteins.
This enzymatic activity is crucial for maintaining proper cellular function and regulating protein stability. Studies have shown that dysregulation of OTUD4 expression can impact cell proliferation, apoptosis, and DNA damage response pathways, highlighting its importance in various disease states, including cancer.Research into the role of OTUD4 in cancer progression and other cellular processes is ongoing, with the hope of uncovering potential therapeutic targets for treating cancer and other diseases. The OTUD4 Polyclonal Antibody provided by AssayGenie offers researchers a reliable tool to further explore the functions of OTUD4 and its potential implications in disease pathology.
Product Name:
OTUD4 Rabbit Polyclonal Antibody
SKU:
CAB15229
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human OTUD4 (NP_001096123.1).
Alternatively spliced transcript variants have been found for this gene. The smaller protein isoform encoded by the shorter transcript variant is found only in HIV-1 infected cells.
Purification Method:
Affinity purification
Gene ID:
54726
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using OTUD4 Rabbit pAb (CAB15229) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
