OTUB1 Rabbit Polyclonal Antibody (CAB11656)
- SKU:
- CAB11656
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | OTUB1 Rabbit Polyclonal Antibody |
SKU: | CAB11656 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human OTUB1 (NP_060140.2). |
Sequence: | MAAE EPQQ QKQE PLGS DSEG VNCL AYDE AIMA QQDR IQQE IAVQ NPLV SERL ELSV LYKE YAED DNIY QQKI KDLH KKYS YIRK TRPD GNCF YRAF GFSH LEAL LDDS KELQ RFKA VSAK SKED LVSQ GFTE FTIE DFHN TFMD LIEQ VEKQ TSVA DLLA SFND QSTS DYLV VYLR LLTS GYLQ RESK FFEH FIEG GRTV KEFC QQEV EPMC KESD HIHI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | OTB1; OTU1; HSPC263; OTUB1 |
Positive Sample: | HeLa,A375,HT-29,293T,Mouse brain,Mouse heart,Mouse kidney,Mouse testis,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 31kDa |
Observed MW: | 37kDa |
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 55611 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |