OTUB1 Rabbit Polyclonal Antibody (CAB10313)
- SKU:
- CAB10313
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | OTUB1 Rabbit Polyclonal Antibody |
SKU: | CAB10313 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human OTUB1 (NP_060140.2). |
Sequence: | ERLE LSVL YKEY AEDD NIYQ QKIK DLHK KYSY IRKT RPDG NCFY RAFG FSHL EALL DDSK ELQR FKAV SAKS KEDL VSQG FTEF TIED FHNT FMDL IEQV E |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | OTB1; OTU1; HSPC263; OTUB1 |
Positive Sample: | 293T,Mouse intestine,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 31kDa |
Observed MW: | 31-35kDa |
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 55611 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |