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OSTN Antibody

SKU:
PACO64881
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
IHC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
$383
Frequently bought together:

Description

OSTN Antibody (PACO64881)

The OSTN Polyclonal Antibody is a valuable tool for researchers studying osteocrin (OSTN), a novel secreted protein linked to skeletal muscle health and metabolism. The antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By specifically binding to OSTN, this antibody enables the detection and analysis of OSTN expression in various cell types, making it an ideal choice for investigations in the fields of physiology, metabolism, and musculoskeletal biology.

OSTN has been identified as a regulator of muscle growth and metabolism, with potential implications for conditions such as sarcopenia, obesity, and metabolic disorders. Its unique role in skeletal muscle function makes it a promising target for research aimed at understanding and developing treatments for these health issues. The accurate detection and analysis of OSTN expression with the OSTN Polyclonal Antibody can provide valuable insights into the physiological functions and therapeutic potential of this important protein.

Product Name:OSTN Antibody
Product Code:PACO64881
Size:50µL
Target Names:OSTN
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:100-1:500
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Recombinant Human Osteocrin protein (28-133aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:>95%, Protein G purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Osteocrin (Musclin) [Cleaved into: Processed Osteocrin], OSTN
Uniprot ID:P61366
Background:Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience (PubMed:27830782). Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex (PubMed:27830782). Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity).
Research Area:Stem Cells

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