OSTM1 Rabbit Polyclonal Antibody (CAB11685)
- SKU:
- CAB11685
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | OSTM1 Rabbit Polyclonal Antibody |
SKU: | CAB11685 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-284 of human OSTM1 (NP_054747.2). |
Sequence: | ALPF GSSP HRVF HDLL SEQQ LLEV EDLS LSLL QGGG LGPL SLPP DLPD LDPE CREL LLDF ANSS AELT GCLV RSAR PVRL CQTC YPLF QQVV SKMD NISR AAGN TSES QSCA RSLL MADR MQIV VILS EFFN TTWQ EANC ANCL TNNS EELS NSTV YFLN LFNH TLTC FEHN LQGN AHSL LQTK NYSE VCKN CREA YKTL SSLY SEMQ KMNE LENK AEPG THLC IDVE DAMN ITRK LWSR TFNC SVPC SDTV P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GL; GIPN; OPTB5; HSPC019; OSTM1 |
Positive Sample: | HeLa,293T,A-549,Raji,B cells,Mouse brain,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome membrane, Single-pass type I membrane protein. |
Calculated MW: | 37kDa |
Observed MW: | 30-37kDa |
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
Purification Method: | Affinity purification |
Gene ID: | 28962 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |