The Osteopontin Rabbit Monoclonal Antibody (CAB19092) is a valuable tool for researchers studying osteopontin, a protein involved in various biological processes, including cell adhesion, migration, and immune regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Osteopontin is a multifunctional protein that plays a role in tissue remodeling, inflammation, and cancer progression. By targeting osteopontin with this monoclonal antibody, researchers can monitor its expression levels and localization in different cell types, aiding in the investigation of its biological functions.
This antibody is particularly useful for studies in immunology, cancer biology, and bone metabolism.Furthermore, understanding the role of osteopontin in disease pathogenesis can provide insights into potential therapeutic strategies for conditions such as cancer, osteoporosis, and inflammatory disorders. By utilizing the Osteopontin Rabbit Monoclonal Antibody (CAB19092), researchers can advance their understanding of osteopontin's involvement in these processes and potentially identify new targets for drug development.
Product Name:
Osteopontin Rabbit Monoclonal Antibody
SKU:
CAB19092
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Osteopontin (P10451).
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6696
Clone Number:
ARC0471
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Osteopontin antibody (CAB19092) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
