The Osteopontin Polyclonal Antibody (CAB1361) is a valuable tool for researchers studying osteopontin, a protein that plays a key role in various physiological processes. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it an ideal choice for applications such as Western blotting. By targeting the osteopontin protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential tool for investigations in the fields of immunology, cancer research, and more.
Osteopontin is a multifunctional protein involved in processes such as cell adhesion, migration, and immune response regulation. Its role in promoting inflammation, tumor growth, and metastasis makes it a promising target for therapeutic interventions in conditions like cancer and inflammatory diseases. By understanding the mechanisms of osteopontin action, researchers can develop strategies to modulate its effects and potentially improve treatment outcomes for these challenging medical conditions.
Product Name:
Osteopontin Rabbit Polyclonal Antibody
SKU:
CAB1361
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 17-314 of human Osteopontin (NP_001035147.1).
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6696
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Osteopontin antibody (CAB1361) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
