Osteopontin/OPN/SPP1 Polyclonal Antibody
- SKU:
- CAB23658
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Osteopontin/OPN/SPP1 Polyclonal Antibody (CAB23658)
The Osteopontin (OPN/SPP1) Polyclonal Antibody is a powerful tool for researchers studying the role of osteopontin in various biological processes. Osteopontin, also known as SPP1, is a glycoprotein found in bone and other tissues that plays a key role in cell adhesion, migration, and signaling.This antibody, raised in rabbits, is highly sensitive and specific for detecting osteopontin in human samples. It is validated for use in Western blot applications, allowing for the detection and analysis of osteopontin levels in different cell types and tissues.Osteopontin has been implicated in a wide range of physiological and pathological processes, including bone metabolism, inflammation, wound healing, and cancer progression.
By studying the expression and function of osteopontin using this antibody, researchers can gain valuable insights into the mechanisms underlying these processes and potentially identify new therapeutic targets for diseases such as cancer and autoimmune disorders.Overall, the Osteopontin (OPN/SPP1) Polyclonal Antibody is a valuable tool for research in immunology, cancer biology, and other fields where osteopontin is known to play a critical role. Its high specificity and sensitivity make it an essential reagent for any lab studying the function of this important glycoprotein.
Product Name: | Osteopontin/OPN/SPP1 Polyclonal Antibody |
Product Code: | CAB23658 |
Reactivity: | Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | RAW264.7 |
Enables extracellular matrix binding activity. Acts upstream of or within several processes, including cellular ion homeostasis; cellular response to leukemia inhibitory factor; and neutrophil chemotaxis. Located in apical part of cell and cytoplasm. Is expressed in several structures, including alimentary system; brain; metanephros; reproductive system; and skeleton. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); biliary atresia; coronary artery disease (multiple); disease of cellular proliferation (multiple); and hepatitis. Orthologous to human SPP1 (secreted phosphoprotein 1).
Immunogen: | Recombinant protein of mouse osteopontin/OPN/SPP1. |
Sequence: | Email for sequence |
Synonyms: | OP, 2AR, Bsp, Eta, Opn, Ric, BNSP, BSPI, Opnl, Apl-1, ETA-1, Spp-1 |
Calculated MW: | 32kDa |
Observed MW: | 58-75kDa |