The Oscar Antibody (PAC064431) is a high-quality polyclonal antibody that specifically targets the CD300A protein, a key cell surface molecule involved in immune regulation. This antibody, produced in rabbits, has been rigorously tested and validated for use in Western blot applications with human samples. By binding to CD300A, researchers can accurately detect and analyze this important protein in various cell types, making it an invaluable tool for studies in immunology and cancer research.CD300A, also known as an immune inhibitory receptor, plays a crucial role in maintaining immune homeostasis by regulating inflammation and suppressing allergic responses.
Its involvement in immune response modulation positions it as a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By gaining a deeper understanding of CD300A's activity, researchers can develop novel therapies that leverage or control immune function in these disease contexts. In summary, the Oscar Antibody is a reliable and effective tool for investigating the role of CD300A in immune regulation and disease pathogenesis, ultimately contributing to the development of innovative treatments for a variety of conditions.
Antibody Name:
OSCAR Antibody (PACO64431)
Antibody SKU:
PACO64431
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:1000-1:5000
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Osteoclast-associated immunoglobulin-like receptor protein (265-279AA)
OSCAR: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. Belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family. 7 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Receptor, misc.Chromosomal Location of Human Ortholog: 19q13.42Cellular Component: plasma membrane; integral to membrane
UniProt Protein Details:
NCBI Summary:
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
