The OSBPL8 Polyclonal Antibody (CAB17816) is specifically designed for research involving OSBPL8, a protein that plays a key role in intracellular lipid transport and metabolism. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By targeting the OSBPL8 protein, this antibody allows for the detection and analysis of OSBPL8 in various cell types, making it an essential tool for studies in lipid biology and cellular metabolism.OSBPL8, also known as oxysterol-binding protein-related protein 8, is involved in the regulation of cholesterol and lipid metabolism within cells. Dysregulation of OSBPL8 has been implicated in various human diseases, including metabolic disorders and cardiovascular diseases.
Understanding the function of OSBPL8 is crucial for unraveling the mechanisms underlying these diseases and developing targeted therapeutic interventions.Overall, the OSBPL8 Polyclonal Antibody (CAB17816) is a valuable tool for researchers interested in studying lipid metabolism, intracellular transport, and the role of OSBPL8 in human health and disease. Its high specificity and sensitivity make it an ideal choice for Western blot applications and other research techniques aimed at elucidating the complex biological functions of OSBPL8.
Product Name:
OSBPL8 Rabbit Polyclonal Antibody
SKU:
CAB17816
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OSBPL8 (NP_065892.1).
This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
114882
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using OSBPL8 Rabbit pAb (CAB17816) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
