The OSBPL6 Polyclonal Antibody (PAC041866) is a vital tool for researchers studying OSBPL6, a protein involved in lipid metabolism and intracellular trafficking. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blotting experiments. By binding specifically to the OSBPL6 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it a valuable asset for research in lipid biology and cell trafficking studies.
OSBPL6, also known as oxysterol-binding protein-related protein 6, plays a crucial role in regulating lipid homeostasis and intracellular lipid transport processes. Dysregulation of OSBPL6 has been linked to various diseases, including metabolic disorders and cancer, making it a promising target for therapeutic interventions. Investigating the function of OSBPL6 is essential for gaining insights into lipid-related diseases and developing potential treatments that target lipid metabolism pathways.
Antibody Name:
OSBPL6 Antibody (PACO41866)
Antibody SKU:
PACO41866
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Oxysterol-binding protein-related protein 6 protein (1-300AA)
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO41866 at dilution of 1:100.
Background:
Weakly binds 25-hydroxycholesterol.
Synonyms:
Oxysterol-binding protein-related protein 6 (ORP-6) (OSBP-related protein 6), OSBPL6, ORP6
UniProt Protein Function:
OSBPL6: a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]Protein type: Unknown functionChromosomal Location of Human Ortholog: 2q32.1Cellular Component: cytosol; nuclear membrane; plasma membraneMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
