The OSBPL3 Polyclonal Antibody (CAB4604) is a valuable tool for researchers studying OSBPL3, a protein involved in intracellular lipid transport and metabolism. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to OSBPL3, the antibody allows for the detection and analysis of this protein in various cell types, making it ideal for studies in lipid biology and metabolism research.OSBPL3, also known as Oxysterol-binding protein-related protein 3, plays a crucial role in maintaining lipid homeostasis within cells by facilitating the transport and sensing of lipids.
Dysregulation of OSBPL3 has been implicated in various metabolic disorders, making it a promising target for therapeutic interventions aimed at treating conditions such as obesity, diabetes, and cardiovascular diseases. Understanding the function of OSBPL3 is essential for developing novel strategies to modulate lipid metabolism and prevent metabolic-related diseases.
Product Name:
OSBPL3 Rabbit Polyclonal Antibody
SKU:
CAB4604
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 370-520 of human OSBPL3 (NP_056365.1).
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. The encoded protein is involved in the regulation of cell adhesion and organization of the actin cytoskeleton. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
26031
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using OSBPL3 antibody (CAB4604) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (AbGn00020)._Exposure time: 1s.
