The ORMDL2 Monoclonal Antibody (PACO36194) is a valuable tool for researchers studying ORMDL2, a protein involved in the regulation of immune responses and inflammation. This antibody, derived from mouse hybridoma cells, exhibits high specificity and sensitivity for the detection of ORMDL2 in human samples, making it an ideal choice for Western blot and immunohistochemistry applications.ORMDL2 is a key player in the modulation of immune function, with implications in diseases such as asthma, inflammatory bowel disease, and autoimmune disorders.
By targeting ORMDL2, researchers can better understand the mechanisms underlying these conditions and potentially identify novel therapeutic strategies. The use of the PACO36194 antibody allows for precise detection and analysis of ORMDL2 expression in various cell types, facilitating advancements in the fields of immunology and disease research.
Immunofluorescent analysis of MCF-7 cells using PACO36194 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human heart tissue using PACO36194 at dilution of 1:100.
Background:
Negative regulator of sphingolipid synthesis.
Synonyms:
ORM1-like protein 2 (Adoplin-2), ORMDL2
UniProt Protein Function:
ORMDL2: Negative regulator of sphingolipid synthesis. Belongs to the ORM family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 12q13.2Cellular Component: endoplasmic reticulumBiological Process: ceramide metabolic process
