Description
ORF73 Monoclonal Antibody [PAT4C11AT] (CPAB0395)
The ORF73 Polyclonal Antibody (CPAB0395) is a valuable tool for researchers studying ORF73, a protein associated with viral infection and replication. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the ORF73 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in virology and infectious disease research.
ORF73, also known as a viral capsid protein, plays a crucial role in the lifecycle of certain viruses by facilitating viral replication and assembly. Understanding the function and interactions of ORF73 is essential for developing antiviral therapies and strategies to combat viral infections. By targeting ORF73 with this antibody, researchers can gain insights into the mechanisms underlying viral pathogenesis and potential targets for intervention.
Product Name: | ORF73 Antibody |
Product Sku: | CPAB0395 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti ORF73 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant ORF73 amino acids 122-329 purified from Ecoli. |
Clone: | PAT4C11AT. |
Reactivity: | Viral |
Applications: | Western Blot, ELISA, Immunohistochemistry |
Purification Method: | ORF73 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2a |
Background: | ORF73 protein of human herpesvirus 8 is a Kaposi''s sarcoma-associated herpesvirus latent protein that is suspected of playing a critical role in modulating viral and cellular gene expression. ORF73 is linked to cellular chromatin and stays on the chromosomes during cell division. ORF73 maintains the viral genomes during cell division by tethering the viral episomes to the chromosomes. ORF73 binds directly to replication origin recognition complexes which are primarily connected with the terminal repeat region of the HHV8 genome. |
Synonyms: | Human herpesvirus 8, HHV8, Kaposi''s sarcoma-associated herpesvirus, KSHV, ORF73. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |