ORC3 Rabbit Polyclonal Antibody (CAB15415)
- SKU:
- CAB15415
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | ORC3 Rabbit Polyclonal Antibody |
SKU: | CAB15415 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ORC3 (NP_036513.2). |
Sequence: | MATS SMSK GCFV FKPN SKKR KISL PIED YFNK GKNE PEDS KLRF ETYQ LIWQ QMKS ENER LQEE LNKN LFDN LIEF LQKS HSGF QKNS RDLG GQIK LREI PTAA LVLG VNVT DHDL TFGS LTEA LQNN VTPY VVSL QAKD CPDM KHFL QKLI SQLM DCCV DIKS KEEE SVHV TQRK THYS MDSL SSWY MTVT QKTD PKML SKKR TTSS QWQS PPVV VILK DMES FATK VLQD FIII SSQH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | LAT; ORC3L; LATHEO; ORC3 |
Positive Sample: | LO2,293T,HeLa,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 82kDa |
Observed MW: | 82kDa |
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Purification Method: | Affinity purification |
Gene ID: | 23595 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |