The OR8I2 Polyclonal Antibody (PACO02445) is specifically designed for research involving the OR8I2 protein, a member of the olfactory receptor (OR) family involved in the sense of smell. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in various applications, including Western blotting.OR8I2 is a crucial player in the olfactory system, responsible for detecting specific odorants and triggering signaling cascades that result in odor perception.
Its role in the sense of smell makes it a key target for studies in sensory perception, neurobiology, and olfactory-related disorders.By using the OR8I2 Polyclonal Antibody, researchers can effectively detect and analyze the OR8I2 protein in different cell types, shedding light on its function and mechanisms of action. This antibody is an essential tool for advancing our understanding of olfactory reception and developing potential therapies for olfactory disorders.
Antibody Name:
OR8I2 Antibody
Antibody SKU:
PACO02445
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Olfactory receptor 8I2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR8I2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1Chromosomal Location of Human Ortholog: 11q12.1Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
