The OR8H3 Polyclonal Antibody (PACO4193) is a valuable tool for researchers studying OR8H3, a member of the olfactory receptor gene family involved in detecting odors. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in various applications, including Western blotting.OR8H3 is a key player in the olfactory system, specifically involved in sensing and processing specific odors. Its role in olfaction makes it a fascinating target for research in areas such as neuroscience, sensory biology, and drug development.
By using the OR8H3 Polyclonal Antibody, researchers can detect and analyze OR8H3 expression in different cell types, enhancing their understanding of olfactory signaling pathways and odor perception mechanisms.Studying OR8H3 can provide insights into how the olfactory system functions and how variations in OR8H3 expression may impact individual odor perception. This information can be instrumental in developing treatments for disorders related to smell and taste, as well as in creating novel strategies for manipulating olfactory responses in various contexts.
Antibody Name:
OR8H3 Antibody
Antibody SKU:
PACO04193
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 8H3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR8H3: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCRChromosomal Location of Human Ortholog: 11q12.1Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
