The OR8B4 Antibody (PACO05894) is a polyclonal antibody designed for research involving the olfactory receptor OR8B4. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.The olfactory receptor OR8B4 plays a critical role in the sense of smell, specifically in detecting certain odor molecules. By targeting this receptor with the OR8B4 Antibody, researchers can better understand the function and activity of OR8B4 in various cell types and tissues.
This makes the antibody ideal for studies in neuroscience, sensory perception, and olfactory research.With its ability to specifically bind to the OR8B4 protein, the OR8B4 Antibody enables the detection and analysis of OR8B4 expression, providing valuable insights into olfactory receptor function and the mechanisms of smell perception. Researchers can use this antibody to investigate the role of OR8B4 in diseases related to sensory perception and olfactory dysfunction, opening up new avenues for therapeutic development and potential treatments.
Antibody Name:
OR8B4 Antibody (PACO05894)
Antibody SKU:
PACO05894
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
ELISA:1:5000, WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the C-terminal region of human Olfactory receptor 8B4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR8B4: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1Chromosomal Location of Human Ortholog: 11q24.2Cellular Component: plasma membraneMolecular Function: odorant binding; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015]
