The OR8B2/OR8B3 Antibody (PAC03849) is a high-quality polyclonal antibody designed for research involving the OR8B2/OR8B3 proteins, which are olfactory receptors responsible for detecting specific odors. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in various applications, including Western blotting. By targeting the OR8B2/OR8B3 proteins, this antibody allows for the detection and analysis of these olfactory receptors in different cell types, making it ideal for studies in sensory biology and olfactory research.
OR8B2 and OR8B3, known as members of the olfactory receptor gene family, play a crucial role in detecting specific odors and triggering olfactory responses. Understanding the function and regulation of these receptors is essential for unraveling the complexities of human olfaction and sensory perception. Research on OR8B2/OR8B3 may also provide insights into odor-related disorders and contribute to the development of novel odor-based therapeutics or applications in various industries.
Antibody Name:
OR8B2/OR8B3 Antibody
Antibody SKU:
PACO03849
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Olfactory receptor 8B2/3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR8B2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11q24.1Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
