The OR6B3 Antibody (PAC064423) is a highly specific monoclonal antibody designed for research involving the olfactory receptor 6B3 protein. This antibody, generated in mice, is optimized for use in immunohistochemistry, immunofluorescence, and flow cytometry applications. It has been validated for its ability to bind specifically to OR6B3, enabling accurate detection and analysis in various tissue and cell types.OR6B3 is a member of the olfactory receptor family, responsible for detecting specific odors and triggering olfactory responses in the body. Research on OR6B3 can provide insights into the mechanisms of olfaction and sensory perception.
By studying the expression and function of OR6B3, researchers can uncover new information about how the sense of smell works and its role in behavior and physiology.Furthermore, understanding the role of OR6B3 may have implications for various industries, including food and beverage, cosmetics, and fragrance. By elucidating the function of this olfactory receptor, researchers may be able to develop new products or enhance existing ones to target specific sensory preferences and improve consumer experiences.
Antibody Name:
OR6B3 Antibody (PACO64423)
Antibody SKU:
PACO64423
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:1000-1:5000, IHC:1:100-1:500
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Olfactory receptor 6B3 protein (259-272AA)
Western Blot. Positive WB detected in: U251 whole cell lysate. All lanes: OR6B3 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38 kDa. Observed band size: 38 kDa.
IHC image of PACO64423 diluted at 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
IHC image of PACO64423 diluted at 1:300 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
OR6B3: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-passChromosomal Location of Human Ortholog: 2q37.3Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
