The OR5T2 Polyclonal Antibody (PAC06415) is specifically designed for research involving OR5T2, a olfactory receptor known for its role in detecting aromas and odors. This antibody, produced in mammals, exhibits high reactivity with samples from various species and is validated for use in applications such as immunofluorescence and immunohistochemistry. By targeting the OR5T2 protein, researchers can effectively visualize and study olfactory receptor activity in different tissues and cell types, which makes it ideal for studies in sensory biology and neurology.OR5T2, a member of the olfactory receptor family, plays a crucial role in detecting and distinguishing different scents, contributing to the sense of smell and taste perception.
Understanding the function and regulation of OR5T2 can provide insights into olfactory processes and sensory perception, with implications for research in pharmacology, neurobiology, and psychology. The potential applications of the OR5T2 antibody in studying olfactory mechanisms make it a valuable tool for investigating sensory-related disorders and developing novel therapies targeting olfactory receptors.
Antibody Name:
OR5T2 Antibody (PACO64415)
Antibody SKU:
PACO64415
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:100-1:500
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Olfactory receptor 5T2 protein (298-310AA)
Immunofluorescence staining of HepG2 cells with PACO64415 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
OR5T2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCRChromosomal Location of Human Ortholog: 11q12.1Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
