The OR5L1/OR5L2 Polyclonal Antibody (PAC003655) is an essential tool for researchers studying olfactory receptor proteins OR5L1 and OR5L2. These cell surface receptors play a key role in the detection of specific odor molecules in the olfactory system. The antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.By targeting the OR5L1 and OR5L2 proteins, this antibody allows for the accurate detection and analysis of these olfactory receptors in a variety of cell types. This makes it an invaluable tool for studies in sensory biology, neuroscience, and pharmacology.
Understanding the function and expression of OR5L1 and OR5L2 is crucial for unraveling the complexities of olfactory perception and developing new strategies for sensory-related disorders.Overall, the OR5L1/OR5L2 Polyclonal Antibody (PAC003655) offers researchers a reliable and specific tool for investigating the role of olfactory receptors in human physiology and pathology. Its versatility and sensitivity make it an ideal choice for a wide range of research applications.
Antibody Name:
OR5L1/OR5L2 Antibody
Antibody SKU:
PACO03655
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Olfactory receptor 5L1/2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR5L1: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11q11Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
