The OR52B6 Polyclonal Antibody (PAC06403) is a valuable tool for researchers studying OR52B6, a G-protein coupled receptor involved in olfactory signaling. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is specifically validated for use in immunofluorescence and immunohistochemistry applications. By binding to the OR52B6 protein, this antibody enables precise and reliable detection and localization within various tissues and cell types.OR52B6, also known as olfactory receptor 52B6, is a key player in the sense of smell, detecting specific odor molecules and triggering downstream signaling cascades.
Its role in olfactory perception makes it a prime target for studies on sensory biology, neurobiology, and scent perception. By investigating the function and expression patterns of OR52B6, researchers can gain insight into how the olfactory system processes and distinguishes different odors, contributing to our understanding of human sensory perception.
Antibody Name:
OR52B6 Antibody (PACO64403)
Antibody SKU:
PACO64403
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:200-1:500
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Olfactory receptor 52B6 protein (18-29AA)
IHC image of PACO64403 diluted at 1:200 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
