The OR51G1 Monoclonal Antibody (PACO05358) is a powerful tool for research on OR51G1, a G protein-coupled receptor involved in olfactory reception. This antibody, produced through a hybridoma cell line, exhibits high specificity and sensitivity in detecting OR51G1 in various experimental settings. Validated for use in immunohistochemistry and immunofluorescence applications, it enables precise localization and visualization of OR51G1 expression in tissues and cells.OR51G1, also known as olfactory receptor 51G1, plays a crucial role in the sense of smell by detecting specific odorants and initiating olfactory signaling pathways.
Understanding the function of OR51G1 is essential for unraveling the complexities of olfactory perception and potentially developing therapeutic interventions for olfactory-related disorders. The OR51G1 Monoclonal Antibody facilitates detailed investigation into the distribution and function of OR51G1, making it an invaluable asset for researchers in the field of sensory biology and neurobiology.
Antibody Name:
OR51G1 Antibody (PACO05358)
Antibody SKU:
PACO05358
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
ELISA:1:5000, WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human Olfactory receptor 51G1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR51G1: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11p15.4Cellular Component: plasma membraneMolecular Function: olfactory receptor activityBiological Process: signal transduction
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
