The OR51E2 Polyclonal Antibody (PACO05414) is a valuable tool for researchers studying OR51E2, a G protein-coupled receptor involved in olfactory sensation. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting OR51E2 in human samples, making it ideal for use in techniques such as Western blotting and immunohistochemistry.OR51E2, also known as olfactory receptor 51E2, plays a crucial role in detecting specific odorants and transmitting signals to the brain for interpretation. Research into OR51E2 function can provide insights into olfactory perception mechanisms and potentially lead to the development of novel approaches for scent-based therapies or diagnostics.
By utilizing the OR51E2 Polyclonal Antibody, researchers can enhance their understanding of olfactory receptor biology and explore the potential applications of targeting OR51E2 in various fields, including neuroscience, sensory biology, and drug discovery. This antibody serves as a reliable tool for investigating the role of OR51E2 in olfactory processes and may pave the way for innovative advancements in olfactory research.
Antibody Name:
OR51E2 Antibody (PACO05414)
Antibody SKU:
PACO05414
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human, Rat
Immunogen:
Synthesized peptide derived from the C-terminal region of human PSGR.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Probable G protein-coupled receptor that is activated by the short chain fatty acids (SCFA) acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure (PubMed:23401498). May also be activated by steroid hormones and regulate cell proliferation (PubMed:19389702). May also function as an olfactory receptor being activated by beta-ionone (PubMed:19389702).
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
