The OR4K14 Polyclonal Antibody (PACO01235) is a valuable tool for researchers studying the olfactory receptor OR4K14, a key player in the sense of smell. This antibody, produced using rabbits, demonstrates high specificity for human samples and has been validated for use in Western blot applications. By binding to the OR4K14 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential reagent for studies in sensory biology and neurobiology.The olfactory receptor OR4K14 plays a crucial role in detecting specific odor molecules, contributing to our sense of smell and overall sensory perception.
Understanding the function of OR4K14 is essential for unraveling the complexities of olfactory sensation and exploring its implications in various physiological and pathological conditions. By targeting OR4K14 with this antibody, researchers can delve deeper into the mechanisms underlying smell perception and potentially uncover new insights into neurological disorders or therapeutic interventions related to olfaction.
Antibody Name:
OR4K14 Antibody
Antibody SKU:
PACO01235
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Monkey
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 4K14.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR4K14: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 14q11.2Cellular Component: integral to membrane; plasma membraneMolecular Function: transmembrane receptor activityBiological Process: detection of chemical stimulus involved in sensory perception; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
