The OR4K14 Polyclonal Antibody (PAC01234) is a valuable tool for researchers studying the OR4K14 protein, a member of the olfactory receptor family involved in odorant detection. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications including Western blotting. By specifically binding to the OR4K14 protein, researchers can confidently detect and analyze its expression in different cell types, making it a versatile tool for studying olfaction and sensory perception.OR4K14, a key player in the olfactory system, plays a crucial role in detecting and distinguishing various odorants in the environment.
Understanding its function and regulation is essential for unraveling the complex mechanisms underlying our sense of smell. With its involvement in olfaction, the OR4K14 protein is of interest in research fields such as neuroscience, sensory biology, and drug discovery.By using the OR4K14 Polyclonal Antibody, researchers can gain valuable insights into the molecular pathways and mechanisms involved in odorant perception, paving the way for advancements in understanding how we perceive and interact with the world around us.
Antibody Name:
OR4K14 Antibody
Antibody SKU:
PACO01234
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 4K14.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR4K14: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 14q11.2Cellular Component: integral to membrane; plasma membraneMolecular Function: transmembrane receptor activityBiological Process: detection of chemical stimulus involved in sensory perception; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
