The OR4C15 Polyclonal Antibody (PAC064391) is a valuable tool for researchers studying OR4C15, a member of the olfactory receptor family involved in the detection of aromatic molecules. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By targeting the OR4C15 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for studies in the fields of olfaction and sensory perception.
OR4C15 is a key player in the olfactory system, responsible for recognizing specific odor molecules and transmitting this information to the brain for processing. Understanding the function and regulation of OR4C15 is crucial for unraveling the complexities of human olfaction and how scent perception impacts behaviors and physiological responses. Research into OR4C15 may also have implications in areas such as fragrance development, food science, and neurological disorders related to olfactory dysfunction.
Antibody Name:
OR4C15 Antibody (PACO64391)
Antibody SKU:
PACO64391
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC, IF
Recommended Dilutions:
IHC:1:200-1:500, IF:1:100-1:500
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Olfactory receptor 4C15 protein (258-268AA)
IHC image of PACO64391 diluted at 1:200 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
Immunofluorescence staining of A549 cells with PACO64391 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IHC image of PACO64391 diluted at 1:200 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
