The OR4A16 Antibody (PACO01228) is a high-quality polyclonal antibody designed for research involving OR4A16, a member of the olfactory receptor gene family. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in various applications, including Western blot and immunohistochemistry.OR4A16 is a G protein-coupled receptor that plays a crucial role in olfactory signal transduction. By binding to specific odor molecules, OR4A16 initiates a cascade of events leading to the perception of smell.
Understanding the function of OR4A16 is essential for research into olfaction and sensory perception.This antibody enables detection and analysis of OR4A16 in different cell types and tissues, making it ideal for studies in neuroscience, sensory biology, and pharmacology. By studying the expression and function of OR4A16, researchers can gain valuable insights into how we perceive and respond to odors, as well as potentially uncovering new therapeutic targets for olfactory disorders and related conditions.
Antibody Name:
OR4A16 Antibody
Antibody SKU:
PACO01228
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 4A16.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR4A16: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11q11Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activity; transmembrane receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
