The OR2T2/OR2T35 Antibody (PAC001226) is a polyclonal antibody designed for research involving OR2T2 and OR2T35, olfactory receptors that play a role in detecting various odors. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in experiments such as Western blotting. By binding to the OR2T2 and OR2T35 proteins, researchers can study their expression and function in different cell types, providing valuable insights into olfactory perception and sensory processing mechanisms.
Olfactory receptors like OR2T2 and OR2T35 are critical for detecting environmental cues and are essential for the sense of smell. Understanding the activation and regulation of these receptors is crucial for unraveling the molecular mechanisms underlying olfaction and how the brain processes odors. By studying OR2T2 and OR2T35, researchers can gain a better understanding of sensory perception and potentially develop new strategies for treating conditions related to olfactory dysfunction.
Antibody Name:
OR2T2/OR2T35 Antibody
Antibody SKU:
PACO01226
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Olfactory receptor 2T2/35.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR2T2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 1q44Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
