The OR2M3 Antibody (PACO03429) is a polyclonal antibody designed for research involving OR2M3, an olfactory receptor protein involved in odorant detection. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in immunohistochemistry applications. It specifically binds to the OR2M3 protein, enabling detection and analysis in various tissues and cell types.OR2M3, a member of the olfactory receptor family, plays a crucial role in the sense of smell by detecting specific odor molecules. Its unique expression pattern and function make it a valuable target for studies in neuroscience, sensory biology, and olfaction research.
Understanding the role of OR2M3 in odor perception can provide insights into the mechanisms underlying smell and potentially lead to the development of new therapies for olfactory disorders.Overall, the OR2M3 Antibody (PACO03429) is a valuable tool for researchers studying olfactory receptors and their role in odorant detection. Its specificity and reactivity make it ideal for investigating the function and localization of OR2M3 in various biological contexts.
Antibody Name:
OR2M3 Antibody
Antibody SKU:
PACO03429
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 2M3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR2M3: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 1q44Cellular Component: integral to membrane; plasma membraneMolecular Function: olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]